Probiotics for Dental Problems

Please note that each trial is not described in detail. In some trials, drugs, prebiotics and/or additional nutrients were provided that may help the beneficial bacteria be more effective. Also the setting, procedure, and dose for each trial are rarely similar. For more details, search for the reference in Google to find the original publication. The simplest way is to copy and paste the title.

Probiotics also have a function in the mouth, which houses many sorts of bacteria including bacteria (salivary Streptococcus mutans) that erode teeth causing cavities. Probiotics for dental problems exist and can counter bad bacteria in the mouth. In these trials, daily probiotics are typically given to young individuals over a period lasting several months if cavity development is to be monitored. In short-term protocols lasting 1-2 months, the prevalence of bad bacteria in the saliva is monitored. Placebo control groups are usually used.

Probiotic SupplementsImprovements Seen in TrialReferences
YakultControlled gingival inflammation1
LactobacilliReduced bad bacteria2
L. rhamnosus
Reduced bad bacteria3
L. rhamnosus GG
L. rhamnosus LC 705
Reduced bad bacteria4
B. lactis BB-12 ATCC27536
L. acidophilus LA-5
Reduced bad bacteria5
L. reuteri ATCC PTA 5289
L. reuteri DSM 17938
No improvement6
B. coagulansReduced bad bacteria3
B. lactis BB-12Reduced bad bacteria7
B. lactis DN-173 010Reduced bad bacteria8
L. paracasei GMNL-33Reduced bad bacteria9
L. rhamnosus hct 70Reduced bad bacteria10
L. rhamnosus GGProtected against cavities11
L. rhamnosus LB-21Protected against cavities
during long intervention (21+ months)
Reduced primary root caries lesions

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment.


1.         Slawik, S. S., I.; Schilke, R.; Nicksch, S.; Weinspach, K.; Stiesch, M.; Eberhard, J. 2011. Probiotics affect the clinical inflammatory parameters of experimental gingivitis in humans. Eur J Clin Nutr 65:857-863.

2.         Montalto, M. V., M.; Marigo, L.; Covino, M.; Graziosetto, R.; Curigliano, V.; Santoro, L.; Cuoco, L.; Manna, R.; Gasbarrini, G. 2004. Probiotic treatment increases salivary counts of lactobacilli: a double-blind, randomized, controlled study. Digestion 69:53-56.

3.         Jindal, G. P., R. K.; Agarwal, J.; Singh, M. 2011. A comparative evaluation of probiotics on salivary mutans streptococci counts in Indian children. Eur Arch Paediatr Dent 12:211-215.

4.         Ahola, A. J. Y.-K., H.; Suomalainen, T.; Poussa, T.; Ahlstrom, A.; Meurman, J. H.; Korpela, R. 2002. Short-term consumption of probiotic-containing cheese and its effect on dental caries risk factors. Arch Oral Biol 47:799-804.

5.         Singh, R. P. D., S. G.; Chawla, A. 2011. Salivary mutans streptococci and lactobacilli modulations in young children on consumption of probiotic ice-cream containing Bifidobacterium lactis Bb12 and Lactobacillus acidophilus La5. Acta Odontol Scand 69:389-394.

6.         Keller, M. K. H., P.; Dahlen, G.; Stecksen-Blicks, C.; Twetman, S. 2012. Probiotic supplements (Lactobacillus reuteri DSM 17938 and ATCC PTA 5289) do not affect regrowth of mutans streptococci after full-mouth disinfection with chlorhexidine: a randomized controlled multicenter trial. Caries Res 46:140-146.

7.         Caglar, E. K., O. O.; Selvi Kuvvetli, S.; Kavaloglu Cildir, S.; Sandalli, N.; Twetman, S. 2008. Short-term effect of ice-cream containing Bifidobacterium lactis Bb-12 on the number of salivary mutans streptococci and lactobacilli. Acta Odontol Scand 66:154-158.

8.         Caglar, E. S., N.; Twetman, S.; Kavaloglu, S.; Ergeneli, S.; Selvi, S. 2005. Effect of yogurt with Bifidobacterium DN-173 010 on salivary mutans streptococci and lactobacilli in young adults. Acta Odontol Scand 63:317-320.

9.         Chuang, L. C. H., C. S.; Ou-Yang, L. W.; Lin, S. Y. 2011. Probiotic Lactobacillus paracasei effect on cariogenic bacterial flora. Clin Oral Investig 15:471-476.

10.       Juneja, A. K., A. 2012. Evaluating the effect of probiotic containing milk on salivary mutans streptococci levels. J Clin Pediatr Dent 37:9-14.

11.       Nase, L. H., K.; Savilahti, E.; Saxelin, M.; Ponka, A.; Poussa, T.; Korpela, R.; Meurman, J. H. 2001. Effect of long-term consumption of a probiotic bacterium, Lactobacillus rhamnosus GG, in milk on dental caries and caries risk in children. Caries Res 35:412-420.

12.       Stecksen-Blicks, C. S., I.; Twetman, S. 2009. Effect of long-term consumption of milk supplemented with probiotic lactobacilli and fluoride on dental caries and general health in preschool children: a cluster-randomized study. Caries Res 43:374-381.

13.       Lexner, M. O. B., S.; Dahlen, G.; Twetman, S. 2010. Microbiological profiles in saliva and supragingival plaque from caries-active adolescents before and after a short-term daily intake of milk supplemented with probiotic bacteria – a pilot study. Oral Health Prev Dent 8:383-388.

14.       Petersson, L. G. M., K.; Hakestam, U.; Baigi, A.; Twetman, S. 2011. Reversal of primary root caries lesions after daily intake of milk supplemented with fluoride and probiotic lactobacilli in older adults. Acta Odontol Scand 69:321-327.