Probiotics Good for Bones and Arthritis

Zebrafish embryos
Probiotics help grow bones in young zebrafish.
This week on BBS: Probiotics increase bone growth in fish via gene expression, Arthritis may benefit from probiotic treatment and French cheese delivers Bifidobacteria.

Strong Bones for Fish

Probiotic supplementation in fish often confers health benefits. Lactobacillus rhamnosus, for instance, enhances reproduction and the development of young Danio rerio (zebrafish), even increasing bone mineralization. Italian scientists have now found out that this happens through increased expression of key genes related to bone growth. The gene expression pattern induced also suggests that L. rhamnosus may also be beneficial for some bone disorders.

Probiotics May Be Relevant for Arthritis

Studies have shown that the intestinal microbiota in rheumatoid arthritis (RA) patients is altered, which indicates that probiotic treatment may be helpful. Scientists from Iran explored this possibility by treating RA patients with Lactobacillus casei 01 for a total of eight weeks in a randomized, double-blind, placebo controlled clinical trial. After the treatment period, the disease activity score was significantly improved along with several immune parameters.

The Cheese Probiotic Survivors

Petit-Suisse cheese (meaning Little Swiss) is a French cream cheese that is made from drained, fermented milk and cream. Brazilian researchers were interested to know if probiotic bacteria added to the cheese (Lactobacillus acidophilus La-5, Bifidobacterium animalis subsp. lactis Bb-12, and Lactobacillus sakei subsp. sakei 2a) could survive extended storage and simulated digestion. Using a novel method of real-time PCR combined with live cell analysis; they were able to determine that the best survivor was B. animalis subsp. lactis Bb-12. Approximately, 73% of the probiotic bacteria survived the simulations.

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