Review: In Search of a Probiotic Yogurt: Gems Amongst the Supermarket Brands?

Milk Aisle
Can good probiotics be found in the dairy aisle near you?
Ever wondered if regular yogurt is just as useful as a probiotic supplement? Or have you wondered if the claims behind special probiotic yogurt brands are true? Read on. The purpose of this article is to give you a better handle on the beneficial bacteria strains found in different yogurt brands along with scientific evidence describing their possible benefits.

If you like yogurt, you’re not alone. Yogurt has become big business in the US with a projected 7 billion market1. Forbes magazine has even noted that a “Yogurt War” has started with even more companies trying to get involved2, including the soda-giant Pepsi1. The reason behind this rise in popularity is, in part, due to the marketing of Greek-style yogurts, now 40% of the total market1. However, even more importantly, there is scientific evidence showing that the bacteria found in yogurt are really good for you. Probiotic yogurt might have real health benefits.


Probiotics are microorganisms that are known to confer a benefit on the host. In other words, probiotics are any kind of small living creature (whether it be a bacterium, fungus or parasite) that makes you healthier. In the case of yogurt, we are strictly speaking about bacterial probiotics. Science is proving that, in general, most bacteria used in yogurt production have probiotic characteristics. However, not all bacteria are alike and neither are the bacteria strains used in commercial yogurts. Some bacteria strains may be more healthful than others.

Yogurt Brands and Bacterial Species

According to the Dairy Reporter, the top four brands in the United States include: Yoplait, Chobani, Stonyfield and Dannon3. All of these brands can be found at a regular supermarket. Interestingly, of these four brands, only Dannon has products that are specifically marketed as probiotic yogurt with special strains. Other brands that are also popular, but may be harder to find, include Fage Total Greek Yogurt, Greek Gods Yogurt, La Yogurt and Voskos Greek Yogurt. The list below provides information about the species/strains used to produce each product.

Yogurt BrandsBacteria Strains
YoplaitLactobacillus bulgaricus
Streptococcus thermophilus

sometimes: Lactobacillus acidophilus
ChobaniLactobacillus acidophilus
Bifidobacterium bifidum
Lactobacillus casei
Stonyfield FarmsLactobacillus bulgaricus
Streptococcus thermophilus
Lactobacillus acidophilus
Bifidobacterium bifidum

sometimes Lactobacillus rhamnosus
DannonLactobacillus bulgaricus
Streptococcus thermophilus

sometimes: Lactobacillus acidophilus
Bifidobacterium lactis
DN-173 010 in Activia
Lactobacillus casei DN-114- 001 in DanActive
YakultLactobacillus casei Shirota
FageLactobacillus bulgaricus
Streptococcus thermophilus
Lactobacillus acidophilus
Bifidobacterium bifidum
Lactobacillus casei
Greek Gods YogurtLactobacillus bulgaricus
Streptococcus thermophilus
Lactobacillus acidophilus
Bifidobacterium bifidum
Lactobacillus casei
La YogurtLactobacillus bulgaricus
Streptococcus thermophilus
Lactobacillus acidophilus
Bifidobacterium bifidum
Lactobacillus casei
Bifidobacterium animalis BB12
Voskos Greek YogurtLactobacillus bulgaricus
Streptococcus thermophilus
Lactobacillus acidophilus
Bifidobacterium bifidum
Lactobacillus casei

Finding probiotic yogurt

Unfortunately, most studies looking at probiotic benefits are designed using a mixture of different bacteria. This makes trying to determine the individual benefits of each strain very difficult. Furthermore, it is possible that the effects of an individual strain are altered when included within a mixture. Therefore, it’s not always a simple situation of “1 + 1 = 2.”

Benefits of the Basic Starters

The most widely used general yogurt culture species are Lactobacillus bulgarus and Streptococcus thermophilus. Additional strains are added for taste, texture or for probiotic benefits. There are several studies that have studied these classical yogurt bacteria on their own. Both of these species are known to survive the gastrointestinal tract4, 5. It is also confirmed that after consumption of these two bacteria, changes can be found in the fecal microbiota6. There are few clinical studies performed with these two species. In a study with non-alcoholic fatty liver disease patients, it was found that they could improve liver enzyme levels7. Additionally, they also boosted the immune system in anorexia patients8 and helped lactose absorption in lactose-intolerant patients9. There are also some studies that suggest replacing baby formula with regular yogurt can help with bouts of infant diarrhea10, 11.

Beyond Simple Yogurt Species

Besides the basic starter strains mentioned previously, Yoplait yogurt only adds L. acidophilus to its mix. This trio is not well investigated in humans and nor are the combinations used in Chobani, Stonyfield Farms, Fage, Greek Gods Yogurt and Voskos Greek Yogurt. The reason is that most researchers prefer to look at more complex mixes with additional species and unique strains that have more exciting effects.

It is important, in this regard, to remember the difference between species and strains. A species is a unique life form: like humans, dogs or cats. Reproduction between species is, in general, not possible. A strain, on the other hand, is like a breed or race. For instance, dogs are classified into breeds. While they can easily produce young through crossbreeding, each breed does have its own unique character. For bacteria, it’s the same, and this is why the majority of probiotics studies need to be examined carefully. You can’t assume that the species tested are the same strains, and this makes comparisons extremely difficult. The only brands of yogurt that have scientifically studied strains are La Yogurt; Dannon’s Activia and DanActive; and Yakult.

Bifidobacterium animalis lactis BB-12 – La Yogurt

While the precise bacteria combination found in La Yogurt hasn’t been scientifically evaluated, there has been a lot of research done on the strain, Bifidobacterium animalis lactis BB-12, which it contains. This strain, in combination with other bacteria, has been used multiple times in clinical trials. However, studies looking at it on its own are more limited.

That B. animalis lactis BB-12 can affect the immune system is quite clear12-14. In general, it appears to lower inflammation. However, it also can boost immune response parameters when given together with an influenza vaccination15. Studies in infants suggest that it may lower respiratory disease incidence16, but other studies show that it does not decrease illness-related school absenteeism17, 18. Despite a vague picture of its individual effectiveness, it is a popular component of many probiotic supplements, and its genome is even sequenced19.

Bifidobacterium lactis DN-173 010 – Activia

The probiotic strain from Dannon’s Activia is also known as the commercial strain, Bifidus regularis. Unlike B. animalis lactis BB-12, this strain has been studied in isolation and appears to be more suited to treating symptoms associated with irritable bowel syndrome (IBS). Initial studies using mouse models of colitis showed that it could have a positive effect on intestinal inflammation20. Several later studies in humans showed that it could help improve constipation21, 22; bloating, intestinal transit23; and even patient gut well-being24.

Lactobacillus casei DN-114 001 – DanActive

Another functional yogurt from Dannon is the DanActive probiotic yogurt, which contains L. casei DN-114 001, also called L. casei Immunitas. The earliest clinical studies with this probiotic strain examined its ability to prevent diarrhea in children, which showed some success25, 26. Possible mechanisms of action include improving the barrier function of the intestines27, 28, harming bad bacteria29, 30, inhibiting bacterial binding31, and directly controlling the intestinal immune response32, 33. Some studies suggest that it might be helpful in Crohn’s disease31-34. However, there is also a side of this strain that boosts immunity. Like B. animalis lactis BB-12, it seems to help influenza vaccination35 and prevent common infections36-38.

Lactobacillus casei Shirota – Yakult

This strain found in Yakult, infamous for being isolated from a scientist’s own fecal matter, is particularly good at treating chronic constipation39. Patients reported seeing improvements as soon as two weeks after consuming the drink daily. This may be an effect of its ability to manipulate the intestinal microflora40, and it even tackles constipation caused by Parkinson’s disese41. Like the other strains, it appears to help prevent common infections42, 43, and also positively alters immune reactions in those with allergy44 and liver disease45. Unlike the other strains, some studies have addressed its ability to play a role in cancer. These projects have shown that L. casei Shirota can reduce carcinogenic metabolites in the colon46 and reduce recurrences of bladder cancer after surgical treatment47.

Supermarket Medicine

While the studies presented here may look impressive, it’s still wise to cultivate a healthy dose of skepticism when going to the grocery store in search of a solution for a health problem. Let me emphasize: if you are really sick, it is imperative that you visit your doctor. On the other hand, if you are just searching for general support for your health, then a quality probiotic yogurt brand could be great for you, and I even know people that swear by some of them.

As you can also see from the studies, most yogurts are designed for taste and texture and not supporting health. It’s not a coincidence that certain strains are more studied than others; strains really do matter. So, if you’re expecting some health benefits from your probiotic yogurt of choice, check the label first and take a quick look at PubMed and see what’s been published.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment.



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